Share Email Opening Title Intern: Clinical Immunology and Bioanalysis Proteomics/Metabolomics   EOE Statement We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.   About the Organization AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information please visit www.astrazeneca.com .   Description AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of small molecule and biologic prescription medicines. AstraZeneca is pioneering innovative research and exploring novel pathways across key therapeutic areas, including respiratory, inflammation and autoimmunity; cardiovascular and metabolic disease; oncology; neuroscience; and infection and vaccines. We are currently seeking candidates who are working towards obtaining a graduate (M.S, PhD, MD/PhD, PharmD) degree in Chemistry, Biochemistry or Pharmaceutical Sciences for an internship during 2020 in the DMPK department supporting clinical and pre-clinical PK/PD, biomarker (proteomics and metabolomics) studies. Potential intern projects: Applications of high-resolution accurate mass (HRAM) spectrometry to: intact mass and proteomic analysis characterization of in vivo biotransformation of biologics proteomics/metabolomics/lipidomics biomarker studies The intern will have the opportunity to learn and utilize state-of-the-art HRAM spectrometry instruments with the goal to discover and validate clinically-relevant biomarkers or understand in vivo biotransformation of biotherapeutics. The intern is expected to perform specific experiments with minor supervision following hands-on training. Assay design and preparation for most assays will be conducted with supervision. Data analysis and interpretation will be conducted with supervision. At the end of the internship the intern is expected to give an oral presentation about their research.   Position Requirements Position Requirements: Essential Requirements: Bachelor’s degree or equivalent in Chemistry, Biochemistry or Pharmaceutical Sciences Strong background in analytical biochemistry/chemistry with emphasis on LC-MS/MS Expertise in MS-based proteomics or metabolomics Hands-on experience with chromatographic separation of complex analytes by LC; high resolution mass spectrometers, protein digestion/metabolite extraction sample preparation Proficiency with mass spectrometry data acquisition and database searching software, as well as spreadsheet, word processing, and graphical computer programs Good organizational, documentation and technical writing skills Good command of English (written and oral) Strong communication and interpersonal skills Desirable Requirements Familiarity with protein or metabolite identification and profiling studies Background in bioinformatics/statistics Familiarity with basic pharmacokinetic or statistical data analyses   Full-Time/Part-Time Seasonal   Location South San Francisco, CA   This position is currently not accepting applications. To search for an open position, please go to http://AstraZenecaPharmaceuticalsInc.appone.com WE ALSO RECOMMEND Other Jobs Within Same Category -- None found -- Other Jobs Within 60 Miles -- None found --

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