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Molecular Pathology/IHC Scientist 

About the Organization Acutis ( is a specialized medical laboratory that complements its hard science with the soft skills of its support teams. This combination allows practitioners to diagnose and treat with greater confidence and with ease.

Acutis serves the medical community and related fields by providing rapid, reliable diagnostic insights that impact clinical decisions in:

-infectious disease

-clinical toxicology for substance use testing and medication monitoring


We are a biomedical specialty laboratory that has no tolerance for error.

A company as thorough as it is principled: dedication to the advancement of medical testing, industry-leading turnaround time, and world-class service.

Every sample we take and every report we relay is prepared with this end in mind:

to provide our customers with the highest level of certainty possible.

With a service-first mindset, specialized laboratory capabilities, and the agility to adapt as next-generation therapies evolve, Acutis stands at the Service of Science.

Additionally, building on our platform of advanced science and technology, we have introduced to healthcare professionals to Acutis Reveal™, molecular tests for infectious diseases. These new tests offer physicians and clinicians a greater degree of certainty than any standard or traditional test can. These new products offer further evidence of Acutis' passion for innovative technologies and strategies.

Acutis conducts pioneering research for diagnostic services. We employ NGS, targeted PCR, LC-MS/MS, enhanced microbiology techniques and algorithm-based software to develop new diagnostic solutions.

EOE Statement We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.  

Acutis is looking for a highly motivated immunohistochemistry (IHC) and in-situ hybridization (ISH) technologist to join our fast-growing team. Under the general direction and supervision of the Technical Director of Molecular Pathology, the Technologist will effectively apply knowledge and skills in developing, optimizing and validating IHC and ISH assays and run them for clinical sample analysis.

Responsibilities for the Molecular Pathology Technologist include but are not limited to:

  • Under the guidance of the function director, develop, optimize, and validate novel immunohistochemistry (IHC) and in-situ hybridization (ISH/FISH/CISH) assays, but also validate, or verify off-shelf kits, for offering to pharmaceutical clinical trials and standard patient care.
  • Fix fresh human biopsy, embed it in paraffin, cut slides, performs H&E, other standard histopathology, IHC and ISH staining.
  • As directed by the function head, search the market to find potential antibodies and other reagents that can be good candidates for a single antibody or multiplex IHC or single probe or dual probe ISH assay.
  • Search the market and/or literature to find materials that can be used for an assay validation and/or as positive and negative quality control for each assay.
  • Perform staining on Ventana instrument but also Dako and/or Leica.
  • Review slides for overall quality of preparation such as staining intensity, proper cover slipping and stain artifacts before sending slides for pathologist review.
  • Participate in sponsor, CRO, and investigator meetings as requested by business development team or project management to address client analytical questions in real time.
  • Draft SOPs, assay validation reports, clinical study reports and other operational documents.
  • Provide the instructions for sample acquisition, processing, storage, shipping, and handling needed for a lab manual.
  • Work with internal and external operation groups to coordinate activities such as sample management, analysis and result reporting.
  • Perform routine preventive maintenance procedures.
  • Maintain accurate work records (i.e., Maintenance Logs, Temperature Logs, etc.).
Position Requirements


  • Bachelors degree in one of the biological sciences.
  • American Society for Clinical Pathology (ASCP) Histotechnologist certification and/or NY State license is preferred.


  • 5+ years of experience in histopathology sample processing and regular staining including H&E.
  • 3+ years of experience in IHC and ISH staining.
  • Experience with Ventana Benchmark stainer is required. Experience with Dako and/or Leica is preferred.
  • Track-records for establishing, developing, optimizing and validating IHC and ISH assays – Experience developing novel assays is preferred.
  • Ability to draft a plan, SOP, and assay validation report.
  • Collaborative and teamwork skills.
Full-Time/Part-Time Full-Time  

This position is currently accepting applications.

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