Share Email Opening Title Principal Scientist Flow Cytometry  About the Organization Acutis (www.Acutis.com) is a specialized medical laboratory that complements its hard science with the soft skills of its support teams. This combination allows practitioners to diagnose and treat with greater confidence and with ease. Acutis serves the medical community and related fields by providing rapid, reliable diagnostic insights that impact clinical decisions in: -infectious disease -clinical toxicology for substance use testing and medication monitoring -oncology We are a biomedical specialty laboratory that has no tolerance for error. A company as thorough as it is principled: dedication to the advancement of medical testing, industry-leading turnaround time, and world-class service. Every sample we take and every report we relay is prepared with this end in mind: to provide our customers with the highest level of certainty possible. With a service-first mindset, specialized laboratory capabilities, and the agility to adapt as next-generation therapies evolve, Acutis stands at the Service of Science. Additionally, building on our platform of advanced science and technology, we have introduced to healthcare professionals to Acutis Reveal™, molecular tests for infectious diseases. These new tests offer physicians and clinicians a greater degree of certainty than any standard or traditional test can. These new products offer further evidence of Acutis' passion for innovative technologies and strategies. Acutis conducts pioneering research for diagnostic services. We employ NGS, targeted PCR, LC-MS/MS, enhanced microbiology techniques and algorithm-based software to develop new diagnostic solutions.   EOE Statement We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.   Description We are seeking Principal Scientist of Flow Cytometry and CTC. This position will report to the Cheif Scientific Officer. Duties Will Include But Not Limited to the Following: Provide expert advice on flow cytometry and circulating tumor cell (CTC)-based biomarker selection, characterization and development for oncology, immunology and infectious diseases. Evaluate standard and emerging circulating cells-based technologies, off-shelf assays and raw reagents to establish test panels for oncology, immunology and infectious diseases. Design, develop, validate and implement low complexity and high complexity multiparameter conventional flow cytometry, florescent image flow cytometry and florescence activate cell sorting panels for drug discovery and patient standard care. Design assay validation or verification protocol, perform the bench work, compile, analyze and interpret data, and draft assay validation report. Draft a lab manual to assure proper sample collection, processing, transportation and storage, and work with the central lab director and operation to coordinate activities such as sample management, tracking and reconciliation. Isolate mononuclear cells from a variety of sample types, including whole blood and bone marrow, for flow cytometry and downstream assays. Manage the budget and resources for the flow cytometry and CTC. Troubleshoot to fix emerging analytical issues or to optimize an assay performance. Optimize and qualify assays for characterization and analytical testing of cell therapy products. Author and review test method SOPs, method development reports, qualification protocols, risk assessments, and transfers methods to partner functions, and represent the Analytical Flow Cytometry team in cross-functional meetings. Responsible for operation and maintenance of flow cytometers.   Position Requirements Education/Qualifications PhD degree in one of the biological sciences. Experience 5-7 years of experience in flow cytometry at a clinical laboratory, Pharma/Biotech and/or academic institutions. Experience in assay development, optimization, qualification, validation, and troubleshooting using platforms including BD and or Beckman-Coulter. Strong scientific background in multi-parameter flow cytometry including cell separation/sorting. Experience in functional assays of immune cell function. Self-organized and operate effectively without significant day-to-day oversight, while following the CSO high level instructions and staying tightly connected to key stakeholders. Basic knowledge in oncology, immunology and/or infectious disease. Experience in mammalian cell culture. Prior experience with cell proliferation, cytokine release, or potency assay development is preferred. Strong technical writing and presentation skills. Must be detailed oriented, well organized, and have strong interpersonal and communication skills.   Full-Time/Part-Time Full-Time   This position is currently not accepting applications. 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