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Title

Summer Intern DMPK 

EOE StatementWe are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.
 
About the Organization AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information please visit www.astrazeneca.com.



 
Description

Location: Waltham, MA/Remote

We are currently seeking rising undergraduate juniors or seniors, master or PhD-level students working towards obtaining a degree in Biology, Biochemistry, or any related field for a 10-12 week internship during the summer of 2022. 

Objectives/Goals of this Position:

Develop cell lines and BA techniques for building in vitro understanding of the disposition and fate of ADC.

Primary Duties:

  • Establish cell lines such as BT-474, NCI-N877 and/or SK-BR-3, for studies with antibody-drug conjugates (ADC).
  • Establish bioanalytical tools to measure levels of warhead and antibody from in vitro cellular assays.
  • Contribute to modeling efforts to derive kinetics for internalization, degradation and efflux rate for tool ADC molecules.
 
Position Requirements
  • Rising undergraduate juniors or seniors, master or PhD-level students working towards obtaining a degree in Biology, Biochemistry, or any related field.
  • Cell culture experience.
  • Bioanalytical tools (LC-MS/MS, ELISA, Absorbance, HRAM-MS).
  • Legal authorization to work in the U.S.
  • Minimum grade point average of 3.0 preferred.
 
Full-Time/Part-Time Seasonal  
Location Waltham, MA  

This position is currently accepting applications.

Apply Now



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