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Title

Analytical Sciences Intern 

EOE StatementWe are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.
 
About the Organization
AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information please visit www.astrazeneca.com .  
Description

Do you want to be a leader who helps define and shape the future?

Are you a game-changer?

We invite you to join our Summer Intern Team– and work with a world-class group of people who are creative, ambitious, and driven to excel. Our Research and Development Scientists are transforming the industry.  

You will be assigned a challenging research project requiring creative thinking, problem solving, and teamwork as you interact with other personnel throughout our winning organization.

In addition, you will have fun while adding value and encountering outstanding career development support.

What are the objectives/goals of the position?

Multi-attribute method (MAM) using a mass spectrometry (MS) has been adopted in our analytical BPD and showed promising benefits providing sensitive and selective information, and potential to reduce the number of arrays required for product quality control. Current peptide mapping method takes more than 6 hours of sample preparation time due to the necessary steps of in-solution tryptic digestion followed by buffer exchange, even the entire sample prep is automated using a robotic system. 

A selected summer intern will evaluate several innovative approaches of protein digestion to reduce the prep time, in turn achieving faster turn-around-time of peptide mapping analysis, which could potentially be utilized in next generation manufacturing.

The goals of this project are following: 1. Evaluate and develop methods using various types of trypsin immobilized beads/magnetic beads from various venders; 2. Evaluate and optimize methods using the high throughput or automated devices; 3. Compare digestion efficiency and MAM focused mass spec data of peptide digests.

What are the primary duties of this position? 

Working in the lab, evaluating sample preparation methods for peptide mapping liquid chromatography mass spectrometry analysis.

 

 
Position Requirements

We are seeking students working towards an undergraduate or graduate degree in Chemistry, Biology, or a related field.

The ideal candidate should have:

  • Laboratory experience
  • Analytical chemistry, biochemistry, and/or protein chemistry experience (preferred).
  • HPLC experience (preferred).
  • Experience working with proteins(preferred).

To participate in the AstraZeneca Intern Program students must meet the following eligibility criteria:

• Legal authorization to work in the U.S.
• Enrollment in a full-time undergraduate or graduate program, returning to the academic program following AstraZeneca assignment
• Minimum grade point average of 3.0 preferred
• At least 18 years of age prior to the scheduled start date
• Completed at least two years of undergraduate studies

 

 
Full-Time/Part-Time Contingent  
Location Gaithersburg, MD  

This position is currently not accepting applications.

To search for an open position, please go to http://AstraZenecaPharmaceuticalsInc.appone.com



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