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Title

Clinical Immunology and Bioanalysis Mass Spectrometry Intern 

EOE StatementWe are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.
 
About the Organization
AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information please visit www.astrazeneca.com .  
Description

AstraZeneca is a global, innovation-driven biopharmaceutical business focusing on the commercialization of biologic prescription medicines. This full-time paid internship opportunity is for the summer of 2019.

Location: South San Francisco, CA

Main Duties and Responsibilities

We are currently seeking candidates who are working towards obtaining a graduate (M.S, PhD, MD/PhD, PharmD) degree in Chemistry, Biochemistry or Pharmaceutical Sciences for an internship during 2019 in the DMPK department supporting clinical and pre-clinical PK/PD and non-clinical toxicology studies.

Potential projects:

Targeted and untargeted metabolomics/lipidomics/proteomics

ADME of small molecules and biologics

Applications of Ion Mobility Spectroscopy to Mass Spectrometry

The intern will have the opportunity to learn and utilize state-of-the-art mass spectrometry instruments within our group with the goal to discover and validate clinically-relevant biomarkers and/or understand ADME properties of small molecule drugs and biotherapeutics. The intern is expected to perform specific assays with minor supervision following hands-on training; however, assay design and preparation for most assays will be conducted with supervision. Data analysis and interpretation will be conducted with supervision. At the end of the internship the intern is expected to give an oral presentation about their research.

Essential Requirements:

Bachelor’s degree in Chemistry, Biochemistry or Pharmaceutical Sciences

Strong background in analytical biochemistry/chemistry with emphasis on LC-MS

Expertise in metabolomics, lipidomics or proteomics

Hands-on experience with chromatographic separation of various analytes by LC and characterization and quantification by MS or MS/MS

Proficiency with mass spectrometry software as well as spreadsheet, word processing, and graphical computer programs

Good organizational, documentation and technical writing skills

Good command of English (written and oral)

Strong communication and interpersonal skills

Desirable Requirements

Familiarity with basic pharmacokinetic data analyses

Familiarity with metabolite identification and profiling studies

 
Position Requirements

Position Requirements:

To participate in the AstraZeneca Intern Program,

Students must meet the following eligibility criteria:
• Legal authorization to work in the U.S.
• Enrollment in a full-time undergraduate or graduate program, returning to the academic program following AstraZeneca assignment
• Minimum grade point average of 3.0 preferred
• At least 18 years of age prior to the scheduled start date

 
Full-Time/Part-Time Full-Time  
Location South San Francisco, CA  

This position is currently not accepting applications.

To search for an open position, please go to http://AstraZenecaPharmaceuticalsInc.appone.com



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