Share Email Opening
Title

Lung Epithelial Intern  

EOE StatementWe are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status or any other characteristic protected by law.
 
About the Organization
AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines, primarily for the treatment of cardiovascular, metabolic, respiratory, inflammation, autoimmune, oncology, infection and neuroscience diseases. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information please visit www.astrazeneca.com .  
Description

Intern: MedImmune RIA

Lung Epithelial Intern

Location: Gaithersburg, MD

MedImmune is the worldwide biologics research and development arm of AstraZeneca, a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of small molecule and biologic prescription medicines. MedImmune is pioneering innovative research and exploring novel pathways across key therapeutic areas, including respiratory, inflammation and autoimmunity; cardiovascular and metabolic disease; oncology; neuroscience; and infection and vaccines.

We are currently seeking candidates who are working towards obtaining a Bachelor’s Degree in Biology or related major for an internship during the summer of 2018. This internship opportunity is with the RIA department.

Human airway diseases such as cystic fibrosis (CF), asthma and chronic obstructive pulmonary disease (COPD) are becoming increasingly prevalent, and mortality from these diseases is rising. One of the major roadblocks in airway disease research is the lack of proper ex vivo models that accurately reflect airway tissue. Importantly, access to airway tissue from patients is limited, and is obtained from individuals that have died, or had their lungs transplanted, which only reflect a snapshot of end-stage disease. Furthermore, animal models of chronic lung disease have limitations that do not reflect human disease. Factors such as high cost and logistical hurdles limit the use of large animal models. An ex vivo model that better reflects disease pathophysiology will advance studies in COPD and other chronic lung diseases, to better understand airway epithelial pathobiology and to test potential therapeutics. In this study, we will utilize human basal stem cells, to develop an airway model that better mimics human physiology and disease than do the models described above. We will develop a novel culture system for translational airway disease modeling and for drug screening applications.

Core Responsibilities:

  • The organoid culture of human basal cells
  • Isolation of genomic DNA and total RNA and gene expression analysis
  • Protein expressing analysis
  • Histological analysis

 
Position Requirements

Position Requirements:

  • Aseptic techniques
  • Imaging techniques
  • Preference for experience with ELISA, PCR
  • Undergraduate Sophomore, Junior, Seniors
  • Minimum GPA of 3.0+
 
Full-Time/Part-Time Seasonal  
Location Gaithersburg, MD  

This position is currently not accepting applications.

To search for an open position, please go to http://AstraZenecaPharmaceuticalsInc.appone.com



WE ALSO RECOMMEND

Other Jobs Within Same Category
-- None found --



Other Jobs Within 60 Miles
-- None found --




 


AppOne.comTM   copyrightŠ1999-2021 HR Services, Inc.
Click here for technical assistance.